Principal Investigator

Daphne J. Holt, MD, PhD received her MD and PhD from the University of Chicago Pritzker School of Medicine. She then went on to complete her clinical training at the MGH/McLean Psychiatry Residency Program and a fellowship in clinical research and neuroimaging at the Athinoula A. Martinos Center for Biomedical Imaging. She has been a faculty member of the MGH Psychiatry Department since 2004, and is also both faculty at the Athinoula A. Martinos Center for Biomedical Imaging and Associate Professor at Harvard Medical School. In addition to running her lab, she also serves as the Co-Director of the MGH Schizophrenia Clinical and Research Program (SCRP) and the Director of the Resilience Enhancement and Prevention Program (REPP), a clinical service focused on developing interventions to increase resilience of youth with risk factors for developing psychiatric illnesses.
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Post-Doctoral Fellows

Tracy Barbour, MD received her medical degree from Wayne State University School of Medicine and completed her residency at the MGH/McLean Adult Psychiatry Residency Program. She practices as a clinician in addition to performing research, and her research interests include studying patients in their first episode of psychosis and at-risk populations and using brain imaging to examine early markers of vulnerability.
Zahra (Mona) Nasiriavanaki, MD received her medical degree from Shahid Beheshti University in Iran. She previously did research at the Institute for Research in Fundamental Sciences (IPM), where she investigated the neural correlates of decision making in reward and punishment conditions using structural brain MRI. Her current research includes studying the peri-personal space in healthy, at-risk, and psychotic patients using functional brain MRI.
Lauren Luther, PhD received her doctorate in Clinical Psychology from Indiana University-Purdue University Indianapolis. Her Ph.D. research focused on the identification and treatment of psychosocial mechanisms (i.e., defeatist beliefs and metacognition) of negative symptoms, particularly reduced motivation, in people with and at risk for schizophrenia-spectrum disorders. Her current research focuses on using neuroimaging to elucidate the neurobiological mechanisms of negative symptoms.

Clinical Research Coordinators

Yushan (Wisteria) Deng, BA received her degree in Psychology from the University of Michigan in 2018, where she completed an undergraduate Honors Thesis studying the mediation effects of anxiety on social functioning among subclinical psychotic population. She has previously worked at Michigan Medicine, where she investigated emotional recognition, reward-processing and gaze perception with ERP and fMRI. Her current research interests lie in the dimensional understanding of clinical comorbidity, especially in relation to early psychosis.
Amritha Harikumar, MA graduated from San Diego State University in 2018, with a master’s in Psychology, concentration in Behavioral / Cognitive Neuroscience. She completed an undergraduate honors thesis focusing on differences in executive functioning in agitated and atypical depressive symptomatology, as well as a master's thesis focusing on functional connectivity differences in ASD and ADHD children. Her current research interests include pursuing interdisciplinary research in behavioral and cognitive neuroscience, functional neuroimaging, and clinical neuropsychological techniques.
Samantha E. Hines, BA graduated with a B.A in psychology from Wheaton College in Massachusetts. She also serves as the First Episode and Early Psychosis Program’s (FEPP) supported education and employment specialist in conjunction to her role as a clinical research coordinator. Samantha’s research interests include the risk for substance use and psychosis, specifically the relationship between marijuana and psychosis, and neuroimaging of the mechanisms of the emotional processing of individuals with a psychotic disorder.
Caroline N. Kale, BA graduated from the University of Texas at Austin with Special Honors in Psychology in 2018, where she completed an undergraduate Honors Thesis exploring the relationship between empathy, bystander intervention in bullying, and the moderating role of testosterone. Additionally, she worked in the UT Austin Laboratory for the Study of Anxiety Disorders on studies investigating social anxiety and PTSD. Her current research interests at MGH include antipsychotic clinical trials for schizophrenia, as well as the use of virtual reality technology for personal space exposure therapy for psychotic illness. 

Program Manager

Leah B. Namey, MPH earned her master's in public health from Boston University's School of Public Health. She is the Sr. Program and Research Manager for the MGH Schizophrenia Clinical and Research Program (SCRP), which encompasses the First Episode and Early Psychosis Program (FEPP) and the Resilience Enhancement and Prevention Program (REPP). In addition, Leah oversees and manages the implementation of numerous clinical trials and manages the program's financial portfolio.

Alumni, Collaborators, & Associated Programs

Mariam Abdelgany - Undergraduate Neuroscience Student at Boston University
Emily A. Boeke, BS - PhD student in Cognition & Perception, New York University
Brittany S. Cassidy, PhD - Post-Doctoral Fellow, Indiana University
Garth Coombs III, BS - PhD student in Cognition, Brain, & Behavior, Harvard University
Stephanie N. DeCross, BA - PhD student in Clinical Psychology, Harvard University
Jessica Mow, BA - PhD student in Clinical Psychology, Boston University
Logan Leathem, BA, BS - PhD student in Clinical Psychology, University of California Los Angeles (UCLA)
Olga Terechina, MD - Psychiatry Resident, Berkshire Medical Center
Lauri Tuominen, MD PhD - Assistant Professor, University of Ottawa, The Royal Ottawa Institute for Mental Health Research
Richard Vettermann - MD student, Technical University Dresden, Germany
Maeve Ward, BA - MD student, Sidney Kimmel Medical College
Rick P. F. Wolthusen - MD student, Technical University Dresden, Germany; Co-founder, On the Move eV
Randy L. Buckner, PhD 
Benjamin K. Brent, MD, MS 
Corinne Cather, PhD 
Bradford C. Dickerson, MD 
Amy H. Farabaugh, PhD 
Maurizio Fava, MD 
Oliver Freudenreich, MD 
Newfei Ho, PhD
Gina R. Kuperberg, MD 
Hesheng Liu, PhD 
Joseph Mandeville, PhD 
Mohammed R. Milad, PhD 
Maren B. Nyer, PhD 
Tracey Petryshen, PhD 
Joshua L. Roffman, MD, MMSc
Bruce R. Rosen, MD, PhD
Benjamin G. Shapero, PhD
Martha E. Shenton, PhD
Roger B. H. Tootell, PhD
Associated Programs
Schizophrenia Clinical & Research Program (SCRP)
First Episode & Early Psychosis Program (FEPP)
Resilience Enhancement & Prevention Program (REPP)
Depression Clinical & Research Program (DCRP)
Jacqueline A. Clauss, MD, PhD received her MD and her PhD from the Vanderbilt University School of Medicine. She is completing her adult psychiatry training at MGH/McLean and will next complete a fellowship in child and adolescent psychiatry at MGH/McLean. Her PhD research focused on the neural basis of inhibited temperament and differences in brain activation during anticipation of social stimuli. Her current research interests are in using neuroimaging and biological markers to understand the basis of risk and resilience for psychiatric disorders.

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