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Lab Director

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Daphne J. Holt, MD, PhD received her MD and PhD from the University of Chicago Pritzker School of Medicine. She then went on to complete her clinical training at the MGH/McLean Psychiatry Residency Program and a fellowship in clinical research and neuroimaging at the MGH Department of Psychiatry and the Athinoula A. Martinos Center for Biomedical Imaging. She has been a faculty member of the MGH Psychiatry Department since 2004, and is an Associate Professor at Harvard Medical School. In addition to overseeing her lab, she also serves as the Co-Director of the MGH Psychosis Clinical and Research Program (PCRP) and the Director of the Resilience and Prevention Program (RAPP), a research program focused on developing and testing interventions to increase the resilience of youth with risk factors for developing psychiatric illnesses.

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Post-Doctoral Fellows

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Jacqueline A. Clauss, MD, PhD received her MD and her PhD from the Vanderbilt University School of Medicine. She completed her adult psychiatry training at MGH/McLean and a fellowship in child and adolescent psychiatry at MGH/McLean. She currently serves as the Medical Director of the Resilience Evaluation-Social Emotional Training (RE-SET) Program in the MGH Department of Psychiatry. Her PhD research focused on the neural basis of inhibited temperament and differences in brain activation during anticipation of social stimuli. Her current research interests are in using neuroimaging and biological markers to understand the basis of risk and resilience for psychiatric disorders.
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Faye McKenna, PhD received her doctorate in Biomedical Imaging from New York University. Her PhD research focused on using advanced diffusion MRI techniques to quantify microstructural and inflammatory changes in the brain in those with psychotic disorders. She is now applying multi-modal neuroimaging to investigate the underlying neural and psychological mechanisms of social isolation and loneliness in those with severe mental illness.

Clinical Research Coordinators

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Daniel S. Johnson, BS received his degree in Psychology from Northeastern University with minors in Behavioral Neuroscience and Theatre in 2020. As part of his degree, Daniel completed a co-op in the CARE lab at McLean Hospital where he studied urgency, cognitive bias, and anhedonia. His current work at MGH focuses on studying biopsychosocial factors related to loneliness and Isolation in those with psychotic disorders.
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Elizabeth S. Eberlin, MA received her graduate degree in Psychology from Boston University in 2022 and received her BS in Psychology from the University of Massachusetts, Amherst in 2019, where she also emphasized a study of math and art. Elizabeth’s MA capstone project explored whether aspects of cognitive functioning could predict work and school outcomes one year later for first episode psychosis populations. In the time between degrees, Elizabeth first worked as a manager for a small tea factory, and then as a Mental Health Specialist on the Schizophrenia/Bipolar Disorders inpatient unit at McLean Hospital. At MGH, Elizabeth coordinates a study assessing the treatment fidelity of first episode psychosis intervention services offered by numerous clinics across Massachusetts. Additionally, she coordinates two studies exploring the utility of novel technologies - a wearable device to measure personal space in-vivo and an artificial intelligence-enabled assessment of mental health in healthcare workers.
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Katherine Dokholyan, BS received her degree in Cognitive Science from Brown University in 2022. As an undergraduate, Katherine was interested in the specific impacts of childhood adversity on adult psychopathology. She studied the mechanisms of risk for stress-related disorders through measures such as exposures and phenotypes related to childhood trauma. At MGH, she is coordinating a study that uses virtual reality to investigate personal space in individuals with and without psychotic disorders.
Francesca de Marneffe, BS received her degrees in Clinical Psychology and Sociology from Tufts University in 2022. As an undergraduate, Francesca worked in a social psychology lab investigating how persuasion techniques can be used to incentivize interracial dialogue and reduce implicit bias. After graduating, she worked at a non-profit clinic in Madrid for people with schizophrenia spectrum disorders. At MGH, Francesca is coordinating an NIH-funded study exploring the effects of loneliness and social isolation on individuals with and without psychotic disorders.

Senior Program Manager

Leah B. Namey, MPH earned her master's in public health from Boston University's School of Public Health. She is the Sr. Program and Research Manager for the MGH Schizophrenia Clinical and Research Program (SCRP), which encompasses the First Episode and Early Psychosis Program (FEPP) and the Resilience and Prevention Program (RAPP). In addition, Leah oversees and manages the implementation of numerous clinical trials and manages the program's financial portfolio.

Faculty

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Nicole DeTore, PhD is an Assistant Professor in Psychology at Massachusetts General Hospital, Harvard Medical School and the Director of Research for the Resilience and Prevention Program. She received her doctoral degree in clinical psychology at Alliant University, and completed her APA internship at the UCSD and the San Diego VA. She completed a three-year research fellowship at Boston University focusing on psychosis-related research. She has additionally worked as a researcher and clinician at UCLA, Harbor UCLA, and Drexel University. Her research focuses on developing preventative behavioral interventions for transdiagnostically at-risk populations, as well as first episode psychosis, schizophrenia, cognition, psychosocial outcomes, and severe mental illnesses.
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Louis Vinke, PhD received his doctorate in Computational Neuroscience from Boston University. His PhD research focused on how visuocortical activity varies across relative and absolute feature dimensions, and employing adaptation as a tool to measure complex population response functions. Currently, he is studying how non-verbal processes important for social communication and motivation differ between clinical and healthy populations, how these processes are supported by basic visual processing, and whether various functional neuroimaging measures can serve as objective markers of these deficits, while also contributing to a systems-level understanding of social behavior.
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Roger Tootell, PhD, Associate Professor of Radiology, HMS, is an internationally recognized authority on the function and organization of the primate visual system. In addition, he was an early pioneer and developer of functional MRI methods. His previous work has investigated a wide range of functions of the visual system, including visual attention and motion perception, which are two functions of interest relevant to his current focus on investigating the neural basis of personal space. He and Dr. Holt have been collaborating since 2009, focusing on the roles of lower-level features, attention/motion, and emotional learning in face processing, interpersonal distance in healthy subjects and in psychosis.

Alumni, Collaborators, & Associated Programs


Alumni
Emily A. Boeke, BS - PhD student in Cognition & Perception, New York University
Brittany S. Cassidy, PhD - Post-Doctoral Fellow, Indiana University
Garth Coombs III, BS - PhD student in Cognition, Brain, & Behavior, Harvard University
Stephanie N. DeCross, BA - PhD student in Clinical Psychology, Harvard University
Jessica Mow, BA - PhD student in Clinical Psychology, Boston University
Logan Leathem, BA, BS - PhD student in Clinical Psychology, University of California Los Angeles (UCLA)
Olga Terechina, MD - Psychiatry Resident, Berkshire Medical Center
Lauri Tuominen, MD PhD - Assistant Professor, University of Ottawa, The Royal Ottawa Institute for Mental Health Research
Richard Vettermann - MD student, Technical University Dresden, Germany
Maeve Ward, BA - MD student, Sidney Kimmel Medical College
Rick P. F. Wolthusen - MD student, Technical University Dresden, Germany; Co-founder, On the Move eV
Yushan (Wisteria) Deng, BA - PhD student in Clinical Psychology, Yale University
Amritha Harikumar, MA - PhD student in Clinical Neuropsychology/Cognitive Neuroscience, Georgia State University
Caroline Kale, BA - MSW student, New York University (NYU)
Samantha Hines, BA - MA student, Worcester Polytechnic Institute
Sarah Zapetis, BS - PhD student in Clinical Psychology, University of Southern California
Yolanda I. Whitaker, BS - Research Coordinator at Mount Sinai Hospital
Jordan Zimmerman, BS - PhD student in Clinical Psychology, Harvard University

Clayton Jeffrey, BS - MS student, McGill University
Tracy Barbour, MD - Medical Director of Transcranial Magnetic Stimulation Clinic in the MGH Psychiatry Department
Gwang-Won Kim, PhD - Chonnam National University Medical School and Hospital, Gwangju, Korea
Zahra (Mona) Nasiriavanaki, MD - Neurology Resident at Cleveland Clinic Florida
Rachel Sussman, BS - Health Data Science S.M. student at the Harvard T.H. Chan School of Public Health
McKain Williams, BS - Senior Clinical Research Assistant at Oregon Health & Science University 
Drew Coman, PhD - Assistant Professor in Psychology in the Department of Psychiatry at MGH and Instructor at HMS 
Collaborators
Randy L. Buckner, PhD 
Benjamin K. Brent, MD, MS 
Corinne Cather, PhD 
Bradford C. Dickerson, MD 
Amy H. Farabaugh, PhD 
Maurizio Fava, MD 
Oliver Freudenreich, MD 
Newfei Ho, PhD
Gina R. Kuperberg, MD 
Hesheng Liu, PhD 
Joseph Mandeville, PhD 
Mohammed R. Milad, PhD 
Maren B. Nyer, PhD 
Tracey Petryshen, PhD 
Joshua L. Roffman, MD, MMSc
Bruce R. Rosen, MD, PhD
Benjamin G. Shapero, PhD
Martha E. Shenton, PhD
Lee S. Cohen, MD
Daniel Fulford, PhD
Supported by
National Institute of Mental Health
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The Sidney R. Baer, Jr Foundation
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The Henry and Allison McCance Center for Brain Health
The MGH Research Scholar Program
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The MGH Executive Committee on Research (ECOR)
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