Selected Publications
Kim GW, Farabaugh AH, Vetterman R, Holmes A, Nyer M, Nasiriavanaki Z, Fava M, Holt DJ. Diminished frontal pole size and functional connectivity in young adults with high suicidality. J Affect Disord. 2022 Aug 1;310:484-492.
Zimmerman J, DeTore NR, Deng W, Burke A, Nyer M, Holt DJ. Worsening of psychotic experiences in college students during the COVID-19 pandemic. Schizophr Res. 2022 Jun 27:S0920-9964(22)00255-9. Epub ahead of print.
Zapetis SL, Nasiriavanaki Z, Luther L, Holt DJ. Neural Correlates of Variation in Personal Space and Social Functioning in Schizophrenia and Healthy Individuals. Schizophr Bull. 2022 Jun 5:sbac052.
Wright AC, Cather C, Mueser KT, Farabaugh A, Terechina O, Fava M, Holt DJ. Relationships among subclinical psychotic symptoms in young adults over time. Psychiatry Res. 2022 May 10;314:114617.
DeTore NR, Luther L, Deng W, Zimmerman J, Leathem L, Burke AS, Nyer MB, Holt DJ. Efficacy of a transdiagnostic, prevention-focused program for at-risk young adults: a waitlist-controlled trial. Psychol Med. 2022 Mar 1:1-10.
Tootell RBH, Zapetis SL, Babadi B, Nasiriavanaki Z, Hughes DE, Mueser K, Otto M, Pace-Schott E, Holt DJ. Psychological and physiological evidence for an initial 'Rough Sketch' calculation of personal space. Sci Rep. 2021 Oct 25;11(1):20960.
Webler RD, Berg H, Fhong K, Tuominen L, Holt DJ, Morey RA, Lange I, Burton PC, Fullana MA, Radua J, Lissek S. The neurobiology of human fear generalization: meta-analysis and working neural model. Neurosci Biobehav Rev. 2021 Sep;128:421-436.
Wright AC, Cather C, Farabaugh A, Terechina O, Pedrelli P, Nyer M, Fava M, Holt DJ. Relationship between cannabis use and psychotic experiences in college students. Schizophr Res. 2021 May;231:198-204.
Nasiriavanaki Z, Barbour T, Farabaugh AH, Fava M, Holmes AJ, Tootell RBH, Holt DJ. Anxious attachment is associated with heightened responsivity of a parietofrontal cortical network that monitors peri-personal space. Neuroimage Clin. 2021;30:102585.
Wang D, Peng X, Pelletier-Baldelli A, Orlov N, Farabaugh A, Nasr S, Eryilmaz H, Fava M, Holmes AJ, Roffman JL, Liu H, Holt DJ. Altered temporal, but intact spatial, features of transient network dynamics in psychosis. Mol Psychiatry. 2021 Jun;26(6):2493-2503.
Burke, A. S., Shapero, B. G., Pelletier-Baldelli, A., Deng, W. Y., Nyer, M. B., Leathem, L., ... & Holt, D. J. (2020). Rationale, Methods, Feasibility, and Preliminary Outcomes of a Transdiagnostic Prevention Program for At-Risk College Students. Frontiers in Psychiatry, 10, 1030.
Barbour, T., Holmes, A. J., Farabaugh, A. H., DeCross, S. N., Coombs, G., Boeke, E. A., ... & Holt, D. J. (2020). Elevated Amygdala Activity in Young Adults With Familial Risk for Depression: A Potential Marker of Low Resilience. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 5(2), 194-202.
Pelletier-Baldelli, A., & Holt, D. J. (2020). Are Negative Symptoms Merely the “Real World” Consequences of Deficits in Social Cognition? Schizophrenia Bulletin, 46(2), 236-241.
DeCross, S. N., Farabaugh, A. H., Holmes, A. J., Ward, M., Boeke, E. A., Wolthusen, R. P., ... & Holt, D. J. (2020). Increased amygdala-visual cortex connectivity in youth with persecutory ideation. Psychological medicine, 50(2), 273-283.
Tuominen, L., Boeke, E., DeCross, S., Wolthusen, R. R., Nasr, S., Milad, M., ... & Holt, D. (2019). The relationship of perceptual discrimination to neural mechanisms of fear generalization. NeuroImage.
Shapero, B. G., Farabaugh, A., Terechina, O., DeCross, S., Cheung, J. C., Fava, M., & Holt, D. J. (2019). Understanding the effects of emotional reactivity on depression and suicidal thoughts and behaviors: Moderating effects of childhood adversity and resilience. Journal of affective disorders, 245, 419-427.
Wolthusen RPF, Coombs III G, Boeke EA, Ehrlich S, DeCross SN, Nasr S, Holt DJ. Correlation between levels of delusional beliefs and perfusion of the hippocampus and an associated network in a non–help-seeking population. Biological Psychiatry CCNI, 2018.
Ho NF, Iglesias JE, Sum MY, Kuswanto CN, Sitoh YY, De Souza J, Hon Z, Fischl B, Roffman JL, Zhou J, Sim K, Holt DJ. Progression from selective to general involvement of hippocampal subfields in schizophrenia. Mol Psych. 2016.
Holt DJ, Boeke EA, Coombs G 3rd, DeCross SN, Cassidy BS, Stufflebeam S, Rauch SL, Tootell RBH. Abnormalities in personal space and parietal-frontal function in schizophrenia. Neuroimage Clin 2015; 9: 233-43.
Mueller S, Wang D, Pan R, Holt DJ, Liu H. Abnormalities in hemispheric specialization of caudate nucleus connectivity in schizophrenia. JAMA Psych. 2015; 72: 552-560.
Holt DJ, Boeke EA, Wolthusen R, Nasr S, Milad MR, Tootell RBH. A parametric study of fear generalization to faces and non-face objects: relationship to discrimination thresholds. Front Hum Neurosci. 2014; 8: 624.
Brent BK, Seidman LJ, Coombs G, Keshevan MS, Moran JM, Holt DJ. Neural responses during social reflection in relatives of schizophrenia patients: relationship to subclinical delusions. Schiz Res. 2014; 157: 292-298.
Holt DJ, Cassidy BS, Yue X, Rauch SL, Boeke EA, Nasr S, Tootell RBH, Coombs III G. Neural correlates of personal space intrusion. J Neurosci. 2014; 34:4123-4134.
Brent BK, Coombs G, Keshevan MS, Seidman LJ, Moran JM, Holt DJ. Subclinical delusional thinking predicts lateral temporal cortex responses during social reflection. Soc Cog Aff Neurosci. 2014; 9: 273-282.
Linnman C, Coombs G, Goff DC, Holt DJ. Lack of insula reactivity to aversive stimuli in schizophrenia. Schiz Res 2013; 143: 150-157.
Holt DJ, Coombs G, Zeidan MA, Goff DC, Milad MR. Failure of neural responses to safety cues in schizophrenia. Arch Gen Psych 2012; 69: 893-903.
Holt DJ, Cassidy BS, Andrews-Hanna JR, Lee SM, Goff DC, Gabrieli JD, Moran JM. An anterior-to-posterior shift in midline cortical activity during self-reflection in schizophrenia. Biol Psych. 2011; 69: 415-423.
Holt DJ, Lakshmanan B, Freudenreich O, Goff DC, Rauch SL, Kuperberg GR. Dysfunction of a cortical midline structure during emotional appraisals in schizophrenia. Schiz Bull 2011; 37: 164-176.
Holt DJ, Lynn SK, Kuperberg GR. Neurophysiological correlates of comprehending emotional meaning in context. J Cog Neurosci 2009; 11: 2245-2262.
Holt DJ, Lebron-Milad K, Milad MR, Rauch SL, Pitman RK, Orr SP, Cassidy BS, Walsh JP, Goff DC. Extinction memory is impaired in schizophrenia. Biol Psych 2009; 65: 455-463.